Find the right hotel in Florence

Top-rated hotels, great locations, and flexible options for every kind of trip.

Check-in
27 Oct 2026
Check-out
28 Oct 2026
Guests
2 guests

Adults:

2

Children:

0

Welcome to Florence

Florence, the birthplace of the Renaissance, captivates with its stunning architecture, world-class art, and vibrant culture. Stroll through charming streets, immerse yourself in history at the Uffizi Gallery, and savor delicious Tuscan cuisine. Experience the magic of Florence for yourself!

Best hotels near Florence Civic Center for event-goers

Perfect for concert-goers, sports fans, and event attendees visiting the Florence Civic Center, these hotels put you minutes away from the action. Guests enjoy free parking, free WiFi, pools, and solid breakfast options - making it easy to arrive refreshed and head straight to the venue.

Quality Inn & Suites Florence Civic Center

Quality Inn & Suites Florence Civic Center

Good (139 reviews)

Florence

from 92 $ avg/night
View ›
Red Roof Inn Florence - Civic Center

Red Roof Inn Florence - Civic Center

Pleasant (417 reviews)

Florence

from 47 $ avg/night
View ›
Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr By Ihg

Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr By Ihg

Fabulous (410 reviews)

Florence

from 141 $ avg/night
View ›
Staybridge Suites - Florence Center By Ihg

Staybridge Suites - Florence Center By Ihg

Superb (708 reviews)

Florence

from 151 $ avg/night
View ›
Homewood Suites By Hilton Florence

Homewood Suites By Hilton Florence

Fabulous (178 reviews)

Florence

from 146 $ avg/night
View ›
Hampton Inn & Suites Florence Center

Hampton Inn & Suites Florence Center

Fabulous (232 reviews)

Florence

from 139 $ avg/night
View ›
Courtyard Florence South Carolina

Courtyard Florence South Carolina

Very Good (262 reviews)

Florence

from 127 $ avg/night
View ›
Days Inn By Wyndham Florence Near Civic Center

Days Inn By Wyndham Florence Near Civic Center

Pleasant (820 reviews)

Florence

from 69 $ avg/night
View ›
Home2Suites By Hilton Florence

Home2Suites By Hilton Florence

Fabulous (352 reviews)

Florence

from 108 $ avg/night
View ›
Residence Inn Florence

Residence Inn Florence

Very Good (107 reviews)

Florence

from 129 $ avg/night
View ›

Boutique hotels in downtown Florence for a cultural weekend

This selection is ideal for culture-focused travelers seeking a characterful base in the heart of Florence for a weekend of museums, historic sites, and local dining. The hotels offer central locations, historic settings, spa access, and refined amenities that complement an immersive cultural itinerary.

Hotel Florence, Tapestry Collection By Hilton

Hotel Florence, Tapestry Collection By Hilton

Very Good (108 reviews)

Florence

from 149 $ avg/night
View ›
Hyatt Place Florence Downtown

Hyatt Place Florence Downtown

Fabulous (422 reviews)

Florence

from 129 $ avg/night
View ›
Hilton Garden Inn Florence

Hilton Garden Inn Florence

Good (144 reviews)

Florence

from 144 $ avg/night
View ›
Aloft By Marriott Florence

Aloft By Marriott Florence

Very Good (354 reviews)

Florence

from 118 $ avg/night
View ›
Park Inn By Radisson Florence, Sc

Park Inn By Radisson Florence, Sc

Very Good (2176 reviews)

Florence

from 84 $ avg/night
View ›

Best family-friendly hotels near Timrod Park and Magnolia Mall

Families looking for a comfortable base near Florence's green spaces and shopping will find plenty of practical options here. These hotels offer family rooms, outdoor and indoor pools, free parking, and complimentary breakfast, keeping every age group happy throughout the stay.

Spark By Hilton Florence North I-95, Sc

Spark By Hilton Florence North I-95, Sc

Good (1250 reviews)

Florence

from 89 $ avg/night
View ›
Hampton Inn & Suites Florence-North-I-95

Hampton Inn & Suites Florence-North-I-95

Fabulous (276 reviews)

Florence

from 134 $ avg/night
View ›
Super 8 By Wyndham Florence

Super 8 By Wyndham Florence

Pleasant (488 reviews)

Florence

from 58 $ avg/night
View ›
La Quinta By Wyndham Florence

La Quinta By Wyndham Florence

Good (1062 reviews)

Florence

from 95 $ avg/night
View ›
Tru By Hilton Florence I-95

Tru By Hilton Florence I-95

Very Good (605 reviews)

Florence

from 119 $ avg/night
View ›
Baymont Inn & Suites

Baymont Inn & Suites

Decent (1258 reviews)

Florence

from 54 $ avg/night
View ›
Springhill Suites Florence

Springhill Suites Florence

Good (470 reviews)

Florence

from 132 $ avg/night
View ›
Days Inn By Wyndham Florence/I-95 North

Days Inn By Wyndham Florence/I-95 North

Pleasant (728 reviews)

Florence

from 50 $ avg/night
View ›

Best budget hotels near Florence Regional Airport for layovers

Perfect for layover travelers who need a comfortable, no-fuss place to rest without overspending. These hotels offer free parking, complimentary breakfast, free Wi-Fi, and easy access to Florence Regional Airport, making short stays simple and stress-free.

Microtel Inn & Suites By Wyndham Florence

Microtel Inn & Suites By Wyndham Florence

Good (737 reviews)

Florence

from 67 $ avg/night
View ›
Econo Lodge Florence - Darlington

Econo Lodge Florence - Darlington

Decent (327 reviews)

Florence

from 52 $ avg/night
View ›
Motel 6-Florence, Sc

Motel 6-Florence, Sc

Decent (160 reviews)

Florence

from 55 $ avg/night
View ›
Suburban Studios Florence I-95

Suburban Studios Florence I-95

Decent (145 reviews)

Florence

from 40 $ avg/night
View ›
Best Western Inn Florence

Best Western Inn Florence

Good (465 reviews)

Florence

from 84 $ avg/night
View ›
Howard Johnson By Wyndham Florence

Howard Johnson By Wyndham Florence

Good (2541 reviews)

Florence

from 64 $ avg/night
View ›
Studio 6 Florence, Sc

Studio 6 Florence, Sc

Decent (79 reviews)

Florence

from 56 $ avg/night
View ›
Affordable Suites Florence

Affordable Suites Florence

Very Good (115 reviews)

Florence

from 90 $ avg/night
View ›

Comfortable mid-range hotels near McLeod Regional Medical Center

This selection is ideal for patients, families, and caregivers who need reliable, affordable lodging within easy reach of McLeod Regional Medical Center. These hotels offer practical amenities like free parking, free Wi-Fi, kitchenettes, and complimentary breakfast to ease the stress of extended medical stays.

Mainstay Suites Florence - Darlington

Mainstay Suites Florence - Darlington

Decent (118 reviews)

Florence

from 71 $ avg/night
View ›
Red Roof Inn Florence, Sc

Red Roof Inn Florence, Sc

Decent (130 reviews)

Florence

from 1000 $ avg/night
View ›
Comfort Suites Florence I-95

Comfort Suites Florence I-95

Good (891 reviews)

Florence

from 109 $ avg/night
View ›
Sleep Inn Florence North

Sleep Inn Florence North

Good (209 reviews)

Florence

from 80 $ avg/night
View ›
Holiday Inn Express & Suites Florence I-95 At Hwy 327 By Ihg

Holiday Inn Express & Suites Florence I-95 At Hwy 327 By Ihg

Very Good (542 reviews)

Florence

from 176 $ avg/night
View ›
Fairfield Inn & Suites By Marriott Florence I-20

Fairfield Inn & Suites By Marriott Florence I-20

Superb (172 reviews)

Florence

from 184 $ avg/night
View ›
Towneplace Suites By Marriott Florence

Towneplace Suites By Marriott Florence

Very Good (120 reviews)

Florence

from 132 $ avg/night
View ›

Browse by accommodation type

Best hotels near Francis Marion University for campus visitors and families

This selection is ideal for families, prospective students, and campus visitors heading to Francis Marion University in Florence, South Carolina. These hotels offer practical amenities like free parking, free WiFi, family rooms, and pools to make your stay comfortable and convenient.

Comfort Inn & Suites Florence Center Area

Comfort Inn & Suites Florence Center Area

Very Good (813 reviews)

Florence

from 113 $ avg/night
View ›
Florence Inn And Suites

Florence Inn And Suites

Pleasant (301 reviews)

Florence

from 63 $ avg/night
View ›
Florence Express Inn

Florence Express Inn

Decent (450 reviews)

Florence

from 38 $ avg/night
View ›
Super 8 By Wyndham Florence Sc I-95 North - Hwy 76

Super 8 By Wyndham Florence Sc I-95 North - Hwy 76

Decent (261 reviews)

Florence

from 49 $ avg/night
View ›
Rodeway Inn Florence Downtown

Rodeway Inn Florence Downtown

Decent (18 reviews)

Florence

from 50 $ avg/night
View ›

Best hotels for history buffs visiting Florence's top museums

This selection is ideal for travelers drawn to Florence's rich Civil War and regional history, looking for a comfortable base between museum visits. Both hotels offer accessible locations in the Florence, SC area with straightforward accommodations suited to explorers focused on the destination rather than the lodging.

Knights Inn Florence Sc

Knights Inn Florence Sc

Florence

from 53 $ avg/night
View ›
Treetop Inn

Treetop Inn

Decent (46 reviews)

Florence

from 50 $ avg/night
View ›

Green space for pets by the exit

I stayed in a first-floor room near the exit, which allowed me to walk my dog on the nearby green areas and use the provided poop bags. I also appreciated the availability of coffee early in the morning during my stay.

J
James J. United States · 2 nights · Single · 1 March 2026 Stayed at Park Inn By Radisson Florence, Sc
9.1
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Outdoor grill by the pool

I grilled dinner at the outdoor kitchen area by the pool after playing corn hole with my family. My suite contained a full-size refrigerator and a stove which I used to prepare meals during my stay. We enjoyed the complimentary dinner and drinks served on Monday, Tuesday, and Wednesday evenings before heading to the fire pit in the backyard.

L
Larry L. United States · 3 nights · Other · 8 August 2026 Stayed at Staybridge Suites - Florence Center By Ihg
10.0
Verified guest Exceptional
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Private bathrooms in the pool room

I swam in the indoor pool and relaxed in the hot tubwith a dedicated bathroom right inside the room so I did not have to leave to change. After walking to a nearby restaurant for dinner, I slept in a super clean room. The next morning I grabbed a go-bag with an apple and a bagel before hitting the road again.

L
Lawrence L. United States · 3 nights · Single · 7 March 2026 Stayed at Hampton Inn & Suites Florence-North-I-95
9.7
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Tesla chargers near the I-95 exit

I plugged my car into the Tesla destination chargers located outside during my three-night stay. Inside the lobby, I played pool on the table while snacking on items from the 24-hour self-service area. My room featured blackout shades that sealed on the edges, which kept the space dark during the morning hours. I enjoyed the indoor pool, which stayed warm throughout my time at the hotel.

M
Malcolm M. United States · 3 nights · Single · 10 February 2026 Stayed at Tru By Hilton Florence I-95
9.1
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Hot tub access until ten in evening

I used the hot tub and the pool, which stayed open until ten in the evening. Each morning, I ate fresh oranges from the breakfast area before heading out to the restaurants near I-95. The front desk staff even handed me a discount coupon for a nearby dinner spot during my stay.

V
Victor V. United States · 3 nights · Single · 14 August 2026 Stayed at Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr By Ihg
9.6
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Gas fireplaces inside the guest suites

I lounged by the gas fireplace in my room after returning from The Mellow Mushroom. The front desk staff handed me a premade breakfast bag when I departedwith fresh juice. I enjoyed the variety of food served at breakfast, which remained stocked until ten on the weekday morning of my departure.

G
George G. United States · 6 nights · Single · 14 August 2026 Stayed at Hampton Inn & Suites Florence Center
9.2
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Consoles inside the game room

My kids played Xbox and Playstation consoles in the game room during our stay. We kept leftovers in our full-size refrigerator and used the full kitchen amenities in our room. I also utilized the complimentary laundry facilities before we headed home.

S
Stephen S. United States · 2 nights · Family With Children · 1 June 2026 Stayed at Home2Suites By Hilton Florence
9.6
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Dog-litter stations on the grounds

I walked my dog at the dog-litter stations positioned on site after arriving at the hotel. My room held a microwave and a fridge, which I used for storing leftovers from the restaurants located right by the mall. I also enjoyed the hot breakfast, where I prepared a waffle alongside scrambled eggs and bacon from 6:30 to 9:30.

S
Stuart S. United States · 1 night · Single · 8 August 2026 Stayed at Comfort Inn & Suites Florence Center Area
9.1
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Terrace view above downtown streets

I spent time on the second floor patio, which overlooks downtown and provides a view of the sunset. I walked to Town Hall for dinner, since the hotel sits across the street from the restaurant. My room felt spacious, and I slept well despite the nearby freight trains. I parked my car in the gated area, which sits one block away from the entrance.

B
Brandon B. United States · 2 nights · Single · 10 May 2026 Stayed at Hyatt Place Florence Downtown
9.2
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Games outdoors on the basketball court

I played on the outdoor basketball court during my two nights at the hotel. My room featured a full kitchen where I heated my own meals. Every morning, I enjoyed the breakfast spread while Genene greeted me in the dining area.

W
William W. United States · 2 nights · Single · 2 August 2026 Stayed at Homewood Suites By Hilton Florence
9.7
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Exposed brick walls in historic rooms

I stayed in a room with original hardwood floors and exposed brick walls, which gave the space a distinct boutique feel. Downstairs in the lobby, I grabbed homemade cookie bars from the free coffee stand after parking my car in the lot across the street. I also enjoyed a meal at Victor's, the restaurant located on the ground floor of this historic building.

S
Susan S. United States · 4 nights · Single · 26 June 2026 Stayed at Hotel Florence, Tapestry Collection By Hilton
9.1
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Swimming in the indoor pool

I swam in the indoor pool before I heated leftovers in the room microwave. Tunisia Ham kept the oatmeal full at breakfastwith egg bites. The building sits in a quiet spot away from the traffic noise of the road.

H
H. H. United States · 2 nights · Single · 5 July 2026 Stayed at Fairfield Inn & Suites By Marriott Florence I-20
9.8
Verified guest Exceptional
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Stovetop cooking in the suite

I used the stovetop in my kitchen to cook a meal with the pots and pans supplied in the cabinets. I walked along the wooded hiking trail next to the building after dinner. Mike corrected my key when the programming failed during my stay.

B
Bruce B. United States · 1 night · Other · 26 April 2026 Stayed at Affordable Suites Florence
9.2
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Arcade games and pool in the lobby

I played at the pool table and arcade in the lobby after my long drive. I relaxed by the fire pit on the back patio when the evening cooled down. My room had two televisions and plenty of outlets for my electronics. I plugged my car into the Tesla chargers available on the hotel during my stay.

L
Louis L. United States · 3 nights · Single · 7 August 2026 Stayed at Aloft By Marriott Florence
9.0
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Whirlpool tubs in the suites

I found a suite with a whirlpool tub which was heaven after a long drive. My children used the heated indoor pool while I picked up complimentary popcorn and candy in the lobby. We also plugged our devices into the multiple USB ports around the room.

J
Johnny J. United States · 2 nights · Family With Children · 18 April 2026 Stayed at Holiday Inn Express & Suites Florence I-95 At Hwy 327 By Ihg
9.0
Verified guest Very Good
  • Verified bookings only
  • Reviewed within 7 days of stay
  • No paid placements, ever

Thank you for your feedback

Thank you for subscribing

Close